Zytiga 250mg tablet: Abiraterone Price & Side effects | Myapplepharma

Zytiga 250mg tablet

• Abiraterone is sold under brand name Zytiga

• Zytiga 250mg is belongs to type of anti-cancer medication that will act by decline the androgen production in the body. Androgen is a male hormone that canmaintance the tumor cell in prostate glands.

• Actually this drug is given by co administration with prednisolone, a steroid which reduce the liability of side effects produced by Abiraterone.

Zytiga 250mg , Zytiga 250mg tablet

DOSAGE

• The prescribed dose of Zytiga 250mg is initial as 4 tablets given orally once daily.

• The drug Zytiga 250mg tablet administrated combination with 5mg prednisolone twice daily in empty stomach.

• Zytiga 250mg tablet given on an empty stomach.

• Food should not be taken for at least 2 hours before and at least 1 hour after the dose of Zytiga Tablets is taken.

• Swallowed whole with water.

• Chew the tablets or Do not crush

MECHANISM OF ACTION

• Androgens are balance the production of malignant in prostate.

• Zytigais belongs to anti androgen drugs, that causes to suppress the enzyme 17α-hydroxylase C 17, 20-lyase (CYP17), it is involves in androgen conglomerate.

• Reduce the serum testosterone level.

• Declined the tumor cell occurred.

PHARMACOKINETICS

Absorption:

• Time to maximum plasma concentration of Zytiga 250mg tablet takes 12 hours.

Distribution:

• Maximum bound to the human plasma protein like albumin and alpha-1 acid glycoprotein.

Metabolism:

• The main two metabolites of Abiraterone in human plasma are Abiraterone sulphate and N-oxide Abiraterone sulphate.

Excretion:

• The drug mainly excreted in 88% feces and 5% in urine

• Half-life of tablet Zytiga 250mg is 12 ± 5 hours.

SAFETY AND WARNING

• Any allergy, serious liver problem or pregnant in patient, Zytiga 250mg therapy should be stopped

• Avoid taking of other medications, i.e prescription, over-the-counter, vitamins, herbal remedies, etc be sure to inform the doctors before the treatment.

• Do not take Aspirin administrated and products containing aspirin till doctor particularly allow the drug.

OVERDOSAGE:

• Zytiga 250mg has no essential antidote, If overdose occurs end treatment with the drug and give general supportive measures such as monitoring arrhythmias and cardiac failure and assess liver function

Zytiga 250mg , Zytiga 250mg tablet

DRUG INTERACTION

• Interaction of Zytiga 250mg with dextromethorphan will raises the Cmax and AUC of dextromethorphan

• Interaction Zytiga 250mg with strong CYP3A inhibitors or inducers , concomitant use with caution because pharmacokinetics is not evaluated.

STORAGE

• The drug stored at 15℃ - 30℃

• Keep the drug in dry place.

MISSED DOSE

• If patient missed the dose of Zytiga 250mg , that missed dose will be skipped and follow the regular dosing schedule.

SIDE EFFECTS

Common effects :

• Fatigue, Arthralgia, Hypertension, Nausea, edema, Hypokalemia, Diarrhea, vomiting, Cough, headache, Glucocorticoid deficiency, Mineral corticoid deficiency, Hepatotoxicity, Hypertension, Decrease in ka level, Adrenocortical insufficiency

• Musculo skeletal and Connective tissue disorders:Joint swelling, discomfort, muscle discomfort

• General Disorder: Oedema

• Cardiac disorders: Hot flush, hypertension, arrhythmias, chest pain, cardiac failure

• GIT disorders: Diarrhea, dyspepsia

• Infections and Infestation:UTI

• Pulmonary disorder: Cough

• Renal:Urinary frequency, nocturia

• Injuries: Fractures.

CONTACT DETAILS

Phone : 9987711567

Email : applepharmaceutical@gmail.com

Email : info@myapplepharma.com

Website : https://myapplepharma.com/abiraterone-250mg.php

                 https://myapplepharma.com/abiraterone.php